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. 2022 Jun 30;9:946556. doi: 10.3389/fnut.2022.946556

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Copyright © 2022 Zhang, Zhou, Zhao, Wang, Zhang and Zhou.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of ferulic acid on glucose metabolism in HFFD-fed rats. (A) The AUC of OGTT; (B) the AUC of ITT; (C) FBG; (D) FBI; (E) HbA1c; (F) HOMA-IR; (G) HOMA-β; (H) QUICKI. Data are presented as mean ± SD. **p < 0.01, vs. Control; ^#p < 0.05, ^##p < 0.01, vs. Model. FAL, low dose of ferulic acid group administered of HFFD mixed with 0.05% ferulic acid; FAH, high dose of ferulic acid administered of HFFD mixed with 0.1% ferulic acid; AP, allopurinol group administered of HFFD mixed with 0.0145% allopurinol.