. 2022 Jun 30;9:946556. doi: 10.3389/fnut.2022.946556

TABLE 3.

Effects of ferulic acid on body weight, food intake, and organ indexes in HFFD-fed rats.

Variable	Control	Model	FAL	FAH	AP
Initial body weight (g)	363.22 ± 21.84	367.46 ± 19.91	365.33 ± 23.46	365.20 ± 30.62	362.00 ± 26.00
Final body weight (g)	618.50 ± 42.14	777.78 ± 47.22^**	700.83 ± 38.33**^,#	690.00 ± 52.86**^,#	695.71 ± 48.94**^,#
Food intake (g/rat/day)	26.54 ± 2.25	21.85 ± 2.47^**	21.90 ± 2.29^**	22.23 ± 2.38^**	21.53 ± 2.14^**
Energy intake (g/rat/day)	368.88 ± 31.26	414.29 ± 46.87^**	415.08 ± 43.35^**	421.12 ± 45.00^**	408.24 ± 40.55^**
Liver index (%)	2.15 ± 0.12	2.38 ± 0.12^**	2.14 ± 0.21^#	2.06 ± 0.17^#	2.21 ± 0.11^#
Kidney index (%)	0.507 ± 0.024	0.424 ± 0.030^**	0.453 ± 0.042^**	0.488 ± 0.021^#	0.461 ± 0.045^*
Perirenal fat index (%)	0.48 ± 0.10	1.09 ± 0.10^**	0.77 ± 0.16**^,#	0.68 ± 0.13**^,#	0.78 ± 0.10**^,#
Epididymal fat index (%)	1.72 ± 0.23	2.91 ± 0.27^**	2.29 ± 0.38**^,#	2.21 ± 0.28**^,#	2.53 ± 0.27^**

Data are presented as mean ± SD. *p < 0.05, **p < 0.01, vs. Control; ^#p < 0.05, vs. Model. FAL, low dose of ferulic acid group administered of HFFD mixed with 0.05% ferulic acid; FAH, high dose of ferulic acid administered of HFFD mixed with 0.1% ferulic acid; AP, allopurinol group administered of HFFD mixed with 0.0145% allopurinol.