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. 2021 Sep;42(9):927–968. doi: 10.15537/smj.2021.42.9.20210126

Table 6.

- Indications for pediatric liver transplantation (LT).

Indications Disease
Chronic liver disease Progressive familial intrahepatic
cholestasis (all types)
Biliary atresia
Autoimmune hepatitis
Sclerosing cholangitis
Caroli syndrome
Wilson’s disease
Cystic fibrosis
Alagille syndrome
Glycogen storage diseases type 1a, 3 and 4
Tight Junction Protein Type 2 (TJP2)
Bile acid coenzyme A: amino acid
N-acyltransferase (BAAT)
Tyrosinemia type 1
Alpha-1-antitrypsin deficiency
Acute liver failure -
Liver tumors -
Unresectable hepatoblastoma (without active extrahepatic disease) -
Metabolic liver disease with life-threatening extrahepatic complications Crigler Najjar Syndrome
Urea cycle defects
Hypercholesterolemia
Organic acidemias
Primary hyperoxaluria