Table 4.
- Analysis of frequency of RPL5 genotype polymorphisms and HVT risk.
| db SNP b153 v2 | Genotype | Patients | Control | P-value* | Unadjusted OR [95% CI] |
|---|---|---|---|---|---|
| n (%) | |||||
| rs138979590 | G/C | 250 (24.5) | 214 (25.2) | Reference | |
| G/T | 260 (25.5) | 210 (24.8) | 0.708 | 1.06 [0.81-1.37] | |
| G/C+G/T | 510 (50.0) | 424 (50.5) | 0.842 | 1.03 [0.82-1.29] | |
| rs558220259 | A/A | 442 (61.7) | 366 (64.8) | Reference | |
| A/G | 144 (20.1) | 113 (20.0) | 0.764 | 1.06 [0.79-1.39] | |
| G/G | 130 (18.2) | 86 (15.2) | 0.173 | 1.25 [0.92-1.7] | |
| rs576892621 | A/A | 466 (65.2) | 378 (67.0) | Reference | |
| A/G | 143 (20.0) | 112 (19.9) | 0.862 | 1.04 [0.78-1.37] | |
| G/G | 106 (14.8) | 74 (13.1) | 0.413 | 1.16 [0.84-1.61] | |
| rs182018447 | G/G | 458 (64.1) | 402 (71.2) | Reference | |
| G/A | 142 (19.9) | 113 (20.0) | 0.543 | 1.10 [0.83-1.46] | |
| A/A | 114 (16.0) | 50 (8.8) | 0.000* | 2.00 [1.39-2.86] | |
| rs559377519 | A/A | 486 (63.7) | 404 (71.5) | Reference | |
| A/T | 148 (19.4) | 113 (20.0) | 0.549 | 1.08 [0.82-1.43] | |
| T/T | 98 (12.9) | 48 (8.5) | 0.004* | 1.69 [1.17-2.45] | |
*
P-values were calculated by chi-square analyses; differences were statistically significant at p<0.05. OR: odds ratio, CI: confidence interval, HVT: hepatic vein thrombosis. Single-variant association analyses was performed.