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. 2022 Jun 30;13:921997. doi: 10.3389/fendo.2022.921997

Table 2.

Association of CVAI, VAI, BMI, WC, WHtR, WHR and LDL-C with hypertension and prehypertension.

Hypertension Pre-hypertension
Model Model 0 Model 1 Model 2 Model 3 Model 0 Model 1 Model 2 Model 3
Variable OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
CVAI
Q1 1 1 1 1 1 1 1 1
Q2 2.186(2.025,2.359)*** 1.811(1.673,1.960)*** 1.807(1.669,1.956)*** 1.768(1.628,1.920)*** 1.896(1.771,2.029)*** 1.705(1.589,1.829)*** 1.703(1.587,1.828)*** 1.613(1.497,1.739)***
Q3 3.765(3.497,4.053)*** 2.672(2.470,2.889)*** 2.648(2.448,2.865)*** 2.523(2.314,2.750)*** 2.990(2.778,3.218)*** 2.469(2.282,2.671)*** 2.464(2.277,2.666)*** 2.233(2.044,2.440)***
Q4 6.840(6.357,7.360)*** 3.850(3.548,4.178)*** 3.782(3.483,4.106)*** 3.475(3.158,3.824)*** 4.452(4.089,4.848)*** 3.214(2.924,3.533)*** 3.185(2.896,3.503)*** 2.747(2.460,3.068)***
VAI
Q1 1 1 1 1 1 1 1 1
Q2 1.287(1.747,1.986)*** 1.408(1.311,1.512)*** 1.416(1.318,1.521)*** 1.371(1.267,1.484)*** 1.227(1.143,1.317)*** 1.358(1.260,1.464)*** 1.365(1.266,1.471)*** 1.327(1.220,1.444)***
Q3 1.562(1.464,1.667)*** 1.751(1.631,1.880)*** 1.752(1.631,1.882)*** 1.632(1.492,1.786)*** 1.595(1.483,1.715)*** 1.823(1.686,1.970)*** 1.829(1.692,1.977)*** 1.702(1.539,1.882)***
Q4 1.863(1.747,1.986)*** 2.247(2.092,2.413)*** 2.227(2.072,2.393)*** 1.895(1.685,2.133)*** 1.899(1.761,2.047)*** 2.247(2.072,2.435)*** 2.246(2.070,2.436)*** 1.889(1.645,2.168)***
LDL,mmol/L
Ideal level 1 1 1 1 1 1 1 1
Appropriate level 1.182(1.120,1.374)*** 1.003(0.945,1.064) 1.015(0.956,1.077) 1.102(1.019,1.191)* 1.278(1.202,1.358)*** 1.133(1.062,1.209)*** 1.138(1.066,1.214)*** 1.173(1.075,1.280)**
Borderline high 1.521(1.428,1.619)*** 1.189(1.109,1.274)*** 1.216(1.133,1.304)*** 1.376(1.229,1.540)*** 1.407(1.306,1.517)*** 1.165(1.075,1.263)*** 1.182(1.090,1.282)*** 1.219(1.069,1.390)**
High 1.863(1.747,1.986)*** 1.272(1.167,1.385)*** 1.297(1.190,1.414)*** 1.548(1.315,1.821)*** 1.684(1.528,1.857)*** 1.342(1.208,1.490)*** 1.359(1.223,1.510)*** 1.399(1.153,1.697)***
BMI, Kg/m2
Normal 1 1 1 1 1 1 1 1
Overweight 2.145(2.039,2.255)*** 1.918(1.817,2.024)*** 1.897(1.797,2.002)*** 1.755(1.660,1.856)*** 1.928(1.821,2.042)*** 1.806(1.701,1.916)*** 1.799(1.695,1.909)*** 1.642(1.544,1.747)***
Obesity 3.587(3.358,3.832)*** 2.913(2.712,3.129)*** 2.857(2.659,3.070)*** 2.562(2.378,2.761)*** 3.002(2.726,3.307)*** 2.649(2.396,2.930)*** 2.620(2.369(2.898)*** 2.300(2.073,2.551)***
WHtR
Normal 1 1 1 1 1 1 1 1
High 2.973(2.804,3.153)*** 2.140(2.010,2.277)*** 2.101(1.974,2.237)*** 1.855(1.739,1.979)*** 1.528(1.457,1.603)*** 1.459(1.389,1.533)*** 1.461(1.390,1.535)*** 1.365(1.296,1.438)***
WC
Normal 1 1 1 1 1 1 1 1
High 2.541(2.427,2.662)*** 1.857(1.766,1.952)*** 1.829(1.739,1.924)*** 1.653(1.569,1.741)*** 2.210(2.093,2.334)*** 1.855(1.751,1.964)*** 1.842(1.739,1.951)*** 1.656(1.560,1.758)***
WHR
Normal 1 1 1 1 1 1 1 1
High 1.743(1.642,1.850)*** 1.772(1.655,1.898)*** 1.735(1.619,1.859)*** 1.536(1.431,1.648)*** 1.465(1.378,1.557)*** 1.629(1.519,1.746)*** 1.612(1.503,1.728)*** 1.413(1.315,1.518)***

Model 0 was unadjusted. Model 1 was adjusted for center, age and sex. Model 2 was additionally adjusted for previously diagnosed CVD, previously diagnosed diabetes, current smoking status, current drinking status, marital status, physical activity. Model 3 was additionally adjusted for eGFR, HbA1C, GGT, AST ALT, TG, TC, HDL-C and SCr.

***P <0.001, **P <0.01, *P <0.05.

CVAI chinese visceral adiposity index, VAI visceral adiposity index, BMI body mass index, WC waist circumference, WHtR waist to height ratio, WHR waist-to-hip ratio, HbA1c glycosylated hemoglobin, ALT alanine transferase, AST aspartate transferase, GGT gamma-glutamyl transferase, TG triglyceride, TC Total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, CVD cardiovascular disease, SCr creatinine.