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. 2022 Jun 30;13:921997. doi: 10.3389/fendo.2022.921997

Table 3.

Association of the CVAI, VAI, BMI, WC, WHtR, WHR, LDL-C index with hypertension and prehypertension by sex.

Hypertension Pre-hypertension
Gender Male Female Male Female
Variable OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
CVAI
Q1 1 1 1 1
Q2 1.441 (1.237,1.679) <0.001 1.916 (1.734,2.116) <0.001 1.622 (1.389,1.894) <0.001 1.610 (1.476,1.756) <0.001
Q3 2.043 (1.760,2.371) <0.001 2.758 (2.474,3.037) <0.001 1.802 (1.532,2.119) <0.001 2.436 (2.185,2.716) <0.001
Q4 2.762 (2.369,3.221) <0.001 3.935 (3.465,4.469) <0.001 2.605 (2.176,3.119) <0.001 2.854 (2.465,3.304) <0.001
VAI
Q1 1 1 1 1
Q2 1.351 (1.190,1.535) <0.001 1.387 (1.252,1.536) <0.001 1.408 (1.205,1.646) <0.001 1.299 (1.174,1.437) <0.001
Q3 1.486 (1.281,1.724) <0.001 1.690 (1.506,1.897) <0.001 1.678 (1.393,2.021) <0.001 1.692 (1.500,1.908) <0.001
Q4 1.720 (1.402,2.110) <0.001 1.933 (1.668,2.239) <0.001 1.814 (1.392,2.364) <0.001 1.851 (1.572,2.180) <0.001
LDL,mmol/L
Ideal level 1 1 1 1
Appropriate level 1.102 (0.964,1.259) 0.154 1.099 (0.998,1.211) 0.056 1.043 (0.884,1.231) 0.619 1.226 (1.106,1.358) <0.001
Borderline high 1.389 (1.137,1.697) 0.001 1.366 (1.191,1.568) <0.001 1.020 (0.788,1.320) 0.882 1.296 (1.112,1.510) 0.001
High 1.451 (1.080,1.948) 0.013 1.575 (1.293,1.917) <0.001 1.171 (0.793,1.729) 0.429 1.498 (1.196,1.875) <0.001
BMI, Kg/m2
Normal 1 1 1 1
Overweight 1.993 (1.805,2.201) <0.001 1.639 (1.531,1.755) <0.001 1.767 (1.567,1.993) <0.001 1.592 (1.481,1.712) <0.001
Obesity 2.751 (2.400,3.153) <0.001 2.461 (2.250,2.693) <0.001 2.569 (2.086,3.163) <0.001 2.209 (1.959,2.492) <0.001
WHtR
Normal 1 1 1 1
High 1.295 (1.179,1.422) <0.001 1.811 (1.670,1.964) <0.001 1.292 (1.177,1.420) <0.001 1.393 (1.309,1.483) <0.001
WC
Normal 1 1 1 1
High 1.749 (1.596,1.917) <0.001 1.587 (1.488,1.692) <0.001 1.546 (1.375,1.740) <0.001 1.668 (1.574,1.810) <0.001
WHR
Normal 1 1 1 1
High 1.461 (1.333,1.601) <0.001 1.692 (1.510,1.895) <0.001 1.369 (1.224,1.530) <0.001 1.459 (1.328,1.604) <0.001

Adjusted for center, age, previously diagnosed CVD, previously diagnosed diabetes, current smoking status, current drinking status, marital status, physical activity, eGFR, HbA1C, GGT, AST ALT, TG, TC, HDL-C and SCr.

CVAI chinese visceral adiposity index, VAI visceral adiposity index, BMI body mass index, WC waist circumference, WHtR waist to height ratio, WHR waist-to-hip ratio, HbA1c glycosylated hemoglobin, ALT alanine transferase, AST aspartate transferase, GGT gamma-glutamyl transferase, TG triglyceride, TC Total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, CVD cardiovascular disease, SCr creatinine.