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. 2022 Jun 30;13:921997. doi: 10.3389/fendo.2022.921997

Table 5.

Association of CVAI, VAI, BMI, WC, WHtR, WHR and LDL-C with hypertension and prehypertension by age.

Hypertension Pre-hypertension
age,year age<55 55≤age<65 age≥65 age<55 55≤age<65 age≥65
Variable OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value OR (95% CI) P value
CVAI
Q1 1 1 1 1 1 1
Q2 2.160 (1.909,2.445) <0.001 1.639 (1.439,1.867) <0.001 1.307 (1.033,1.654) 0.026 1.679 (1.517,1.859) <0.001 1.701 (1.503,1.924) <0.001 1.308 (0.987,1.732) 0.061
Q3 3.325 (2.888,3.827) <0.001 2.386 (2.089,2.725) <0.001 1.738 (1.387,2.178) <0.001 2.430 (2.126,2.778) <0.001 2.317 (2.018,2.661) <0.001 1.848 (1.398,2.442) <0.001
Q4 4.658 (3.929,5.523) <0.001 3.328 (2.878,3.849) <0.001 2.564 (2.036,3.227) <0.001 2.997 (2.464,3.596) <0.001 3.158 (2.659,3.752) <0.001 2.068 (1.542,2.771) <0.001
VAI
Q1 1 1 1 1 1 1
Q2 1.438 (1.251,1.652) <0.001 1.342 (1.189,1.515) <0.001 1.319 (1.124,1.548) 0.001 1.371 (1.216,1.547) <0.001 1.362 (1.188,1.562) <0.001 1.137 (0.897,1.442) 0.289
Q3 1.796 (1.533,2.104) <0.001 1.541 (1.344,1.768) <0.001 1.585 (1.314,1.911) <0.001 1.892 (1.637,2.187) <0.001 1.592 (1.354,1.873) <0.001 1.437 (1.073,1.925) 0.015
Q4 2.309 (1.888,2.825) <0.001 1.778 (1.485,2.219) <0.001 1.683 (1.307,2.167) <0.001 2.024 (1.663,2.464) <0.001 2.037 (1.625,2.554) <0.001 1.130 (0.753,1.696) 0.556
LDL,mmol/L
Ideal level 1 1 1 1 1 1
Appropriate level 1.101 (0.959,1.266) 0.173 1.082 (0.961,1.219) 0.191 1.062 (0.908,1.242) 0.451 1.203 (1.060,1.365) 0.004 1.211 (1.054,1.392) 0.007 0.961 (0.754,1.224) 0.748
Borderline high 1.365 (1.113,1.674) 0.003 1.320 (1.116,1.562) 0.001 1.409 (1.117,1.777) 0.004 1.225 (1.009,1.487) 0.04 1.320 (1.076,1.619) 0.008 0.966 (0.666,1.401) 0.856
High 1.687 (1.257,2.265) <0.001 1.540 (1.212,1.956) <0.001 1.288 (0.917,1.809) 0.144 1.418 (1.062,1.892) 0.018 1.492 (1.106,2.011) 0.009 1.195 (0.692,2.064) 0.522
BMI, Kg/m2
Normal 1 1 1 1 1 1
Overweight 1.998 (1.802,2.214) <0.001 1.678 (1.542,1.825) <0.001 1.588 (1.422,1.773) <0.001 1.706 (1.559,1.867) <0.001 1.623 (1.471,1.791) <0.001 1.390 (1.173,1.647) <0.001
Obesity 3.266 (2.863,3.725) <0.001 2.349 (2.095,2.633) <0.001 2.030 (1.750,2.355) <0.001 2.648 (2.275,3.081) <0.001 2.037 (1.722,2.409) <0.001 1.896 (1.452,2.476) <0.001
WHtR
Normal 1 1 1 1 1 1
High 2.042 (1.832,2.276) <0.001 1.846 (1.675,2.035) <0.001 1.651 (1.427,1.910) <0.001 1.507 (1.394,1.629) <0.001 1.349 (1.243,.464) <0.001 0.993 (0.865,1.139) 0.915
WC
Normal 1 1 1 1 1 1
High 1.843 (1.678,2.024) <0.001 1.621 (1.499,1.754) <0.001 1.521 (1.367,1.691) <0.001 1.769 (1.619,1.932) <0.001 1.665 (1.514,1.831) <0.001 1.421 (1.211,1.668) <0.001
WHR
Normal 1 1 1 1 1 1
High 1.648 (1.457,1.864) <0.001 1.570 (1.412,1.747) <0.001 1.392 (1.203,1.612) <0.001 1.467 (1.324,1.625) <0.001 1.385 (1.234,1.555) <0.001 1.411 (1.146,1.737) 0.001

Adjusted for center, sex, previously diagnosed CVD, previously diagnosed diabetes, current smoking status, current drinking status, marital status, physical activity, eGFR, HbA1C, GGT, AST ALT, TG, TC, HDL-C and SCr.

CVAI chinese visceral adiposity index, VAI visceral adiposity index, BMI body mass index, WC waist circumference, WHtR waist to height ratio, WHR waist-to-hip ratio, HbA1c glycosylated hemoglobin, ALT alanine transferase, AST aspartate transferase, GGT gamma-glutamyl transferase, TG triglyceride, TC Total cholesterol, LDL-C low-density lipoprotein cholesterol, HDL-C high-density lipoprotein cholesterol, eGFR estimated glomerular filtration rate, CVD cardiovascular disease, SCr creatinine.