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In vitro PTK-BAA degradation. Polymer samples were incubated for 72h in escalating doses of H2O2 and evaluated by (A) NMR, indicating that the characteristic thioketal peak underwent dose-dependent degradation. (B) Polymer samples incubated in 10 mM H2O2 and evaluated by MALDI-TOF also demonstrated the complete disappearance of higher molecular weight signal and generated species corresponding with predicted polymer degradation products.
