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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: Adv Healthc Mater. 2021 Mar 18;10(9):e2001941. doi: 10.1002/adhm.202001941

Figure 6.

Figure 6.

Varying the PAA polyanion molecular weight (450, 5, or 1.8 kDa) in BMP-2 / PTK-BAA films (A) does not appreciably change the total BMP-2 loading as visualized by fluorescence imaging of films with Cy5-labeled protein. However, PAA1.8 samples (B) display significantly more sensitivity to oxidation via BMP-2 release at both 1 mM and 0.1 mM H2O2 compared against higher molecular weight PAA formulations (n=3 per treatment; *p<0.05, **p<0.005, ***p<0.0005 for 1 mM H2O2 vs PBS; #p<0.05 for 0.1 mM H2O2 vs PBS). All samples featured 30 tetralayer films constructed on PLGA scaffolds.