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. Author manuscript; available in PMC: 2023 Jul 11.
Published in final edited form as: Cancer Cell. 2022 Jun 2;40(7):720–737.e5. doi: 10.1016/j.ccell.2022.05.006

Figure 5: Exercises sensitizes pancreatic cancer to α-PD1.

Figure 5:

a-e. WT mice were injected orthotopically and exercise was started at Day 1. Mice were treated with IgG or α-PD-1 blocking antibody. Day 21 tumors were assessed by FC for CD3 (a), CD8/CD4 (b), Ki67, IFNγ, GZMB, and T-bet (c) and IL-15Rα (d) on CD8 T cells. Tumor images and weights are shown (e). Each dot = one tumor (n=7–9). Experiment was repeated three times. (p > 0.05 = ns, p < 0.05 = *, p < 0.01 = **, p < 0.001 = ***, p < 0.0001 = ****). See Supp. 7