Table 1.
Transcribed ultraconserved region in gastric cancer
|
T-UCR name
|
Location
|
Orientation
|
Expression in gastric cancer
|
Biological or molecular functions in gastric cancer
|
Ref.
|
| Uc.63+ | Chr.2 | Sense | Downregulated | Associated with the classification and progression of gastric cancer | [14] |
| Uc.118 | Chr.3 | Antisense | Downregulated | - | [16] |
| Uc.158 | Chr.5 | Antisense | Downregulated | - | [16] |
| uc.160 | Chr.5 | Sense | Downregulated | Inhibits cell proliferation and promotes apoptosis in AGS and SGC-7901 cell lines, promoting gastric cancer tumourigenesis | [15,17] |
| Uc.241 | - | - | Downregulated | - | [16] |
| Uc.244 | Chr.8 | Sense | Down/upregulated | - | [16,23] |
| Uc.249 | Chr.9 | Sense | Down/upregulated | - | [16,23] |
| Uc.252 | Chr.9 | Antisense | Down/upregulated | - | [16,23] |
| Uc.261 | Chr.9 | Sense | Down/upregulated | - | [16,23] |
| Uc.282 | Chr.9 | Sense | Down/upregulated | - | [16,23] |
| Uc.283 | - | - | - | - | [16] |
| Uc.346 | Chr.12 | - | Downregulated | - | [23] |
| Uc.359 | Chr.14 | Antisense | Down/upregulated | - | [16,23] |
| Uc.416 | - | Antisense | Upregulated | Promotes proliferation in MKN-74 cell line, promoting gastric cancer tumourigenesis | [16] |
T-UCR: Transcribed ultraconserved region.