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Analysis of pathogenic mutation sites in preoperative feces
|
Gene
|
Location
|
Amino acid mutation
|
Mutation frequency
|
N
|
M
|
| TP53 | Exon 5 | C176Y | 1 | ||
| F134V | 1 | ||||
| Exon 6 | R1961 | 1 | |||
| Exon 7 | N235D | 1 | |||
| R248Q | 3 | ||||
| G245C/S | 2 | ||||
| Exon 8 | R273H/C | 3 | 12/27 | 10/16 | |
| KRAS | Exon 2 | G12D/V | 5 | ||
| G13D | 1 | ||||
| Exon 3 | Q61H | 1 | |||
| A59T | 1 | 8/11 | 7/10 | ||
| APC | Exon 17 | R14501 | 1 | ||
| Q8861 | 1 | ||||
| Q12941 | 1 | 3/3 | 3/3 |
Indicates stop codon.
N: Pathogenic sites/total mutation sites; M: Number of pathogenic cases/total number of mutation cases.
