TABLE 2.

Suspicious radiologic findings of benign versus possible early gallbladder cancer

Gallbladder pathology	Transabdominal US or EUS 8	CT	MRCP 27
Hyperplastic, inflammatory, fibrous, granulomatous polyps	Low echogenicity	Small, rounded intraluminal lesions 28	Homogenously low T1 and T2 signals Homogenous T1 postcontrast enhancement
Cholesterol polyps	Highly echogenic punctate foci	Hounsfield unit similar to bile 28	Homogenously low T1 and T2 signals
Adenoma	Solid echogenicity Multiple microcystic spaces	Small enhancing polypoid lesion, homogenous texture 28	Homogenous T1 postcontrast enhancement
Adenomyomatosis	Cystic anechoic foci and comet enhancements	Gallbladder wall thickening Rokitansky‐Aschoff sinuses 29	Focal intramural T1 and T2 signals with late postcontrast homogenous enhancement
Xanthogranulomatous inflammation	Combination of hyperechoic and hypoechoic intramural signals	Intact mucosal lining associated with diffuse wall thickening and pericholecystic fat stranding 9	Diffuse gallbladder wall thickening with contrast enhancement and with or without intramural abscesses
Gallbladder carcinoma	Heterogenous, irregular echogenicity	Discontinuous mucosa with irregular masses and wall thickening with or without hepatic involvement 9	Protruding mass or wall thickening that is hyperintense on T2‐ but not T1‐weighted signals