Table 1. Input parameters to the numerical model.
Parameter Name | Units | Min Value | Max Value | Step Size | # of Values |
---|---|---|---|---|---|
Peak Inspiratory Pressure (PIP) | cmH![]() |
20 | 50 | 1 | 31 |
Positive End-Expiratory Pressure (PEEP) | cmH![]() |
5 | 20 | 1 | 16 |
Inspiratory to Expiratory Ratio (I:E) | ratio | 1:3 | 1:1 | fraction | 7 |
Respiratory Rate (RR) |
![]() |
10 | 30 | 1 | 21 |
Pulmonary Compliance |
![]() |
10 | 100 | 1-2 | 46-91 |
Endotracheal Tube (ET) Diameter | mm | 6 | 8.5 | 0.5 | 6 |
Resistor Radii | mm | 2.5 | 5.5 | 1 | 7 |
Final parameters, along with the minimum, maximum, and step size, and discrete values explored, that were required for the large parameter sweep. Step sizes were determined so that an incremental change resulted in less than a 5% change in delivered tidal volumes. The top four parameters are ventilator settings (PIP, PEEP, I:E, RR), the next two are patient-specific considerations (Compliances and ET tube size), and the final one is a circuit configuration parameter (Resistor size).