Table 3.
Estimates of the association between in utero famine exposure group (late, mid, early) compared to participants that were not exposed to famine during gestation and thyroid function (TSH and FT4) tests in a thyroid disease free subsample (n=675).
| Model 1a (n=675) | Model 2b (n=675) | Model 3c (n=675) | Model 1d Men (n=341) | Model 1e Women (n=334) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Late | Mid | Early | Late | Mid | Early | Sex | Sex*Late | Sex*Mid | Sex*Early | Late | Mid | Early | Late | Mid | Early | ||
| TSH | Estimate | 0.0 | -0.01 | 0.01 | 0.0 | -0.02 | 0.01 | 0.05 | -0.01 | -0.09 | -0.07 | 0.01 | 0.03 | 0.05 | -0.01 | -0.06 | -0.02 |
| 95% CI | [-0.03, 0.04] |
[-0.04, 0.02] |
[-0.03, 0.05] |
[-0.03, 0.03] |
[-0.05, 0.02] |
[-0.03, 0.05] | [0.03, 0.08] | [-0.07, 0.05] |
[-0.14,
-0.02] |
[-0.14, 0.01] | [-0.03, 0.04] | [-0.01, 0.08] |
[-0.004, 0.10] | [-0.05, 0.04] |
[-0.10,
-0.01] |
[-0.08, 0.04] | |
| FT4 | Estimate | -0.07 | -0.08 | -0.19 | -0.04 | 0 | -0.16 | -0.73 | 0.08 | 0.56 | 0.98 | -0.07 | -0.31 | -0.65 | 0.01 | 0.26 | 0.34 |
| 95% CI | [-0.57, 0.43] |
[-0.60, 0.45] |
[-0.82, 0.44] |
[-0.53, 0.46] | [-0.52, 0.52] |
[-0.78, 0.47] |
[-1.09,
-0.38] |
[-0.71, 1.16] | [-0.37, 1.59] | [-0.06, 2.30] | [-0.78, 0.63] |
[-1.10, 0.49] | [-1.56, 0.25] | [-0.68, 0.70] | [-0.44, 0.95] | [-0.54, 1.19] | |
Bolded values indicate a p-value <0.05.a Crude model with only famine exposure group; b model 1 also adjusted for sex. c model 1 adjusted for sex and includes an interaction term between sex and famine exposure group. d and e are a crude model with famine exposure groups only in sex-stratified sub-samples.