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. Author manuscript; available in PMC: 2023 Jun 23.
Published in final edited form as: Nat Metab. 2022 Jun 23;4(6):759–774. doi: 10.1038/s42255-022-00585-x

Extended Data Fig. 7. CCL18-induced upregulation of transcription factors.

Extended Data Fig. 7.

MDM from healthy individuals and RA patients were induced with M-CSF over 6 days and differentiated with LPS/IFN-γ. Color scales are presented by fold change.

a. Gene expression profiling for 20 transcription factors in Mϕ treated with rhCCL18 (50 ng/mL, n=5) or vehicle (n=5) for 48h. Transcripts were quantified by RT-PCR.

b. Gene expression of 20 transcription factors in Mϕ generated from controls and RA patients. mRNA expression was measured by RT-PCR.