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Fructose increases expression of hippocampal and hypothalamic complement components. In the hypothalamus, C4b was significantly elevated in fructose-fed animals (a) without changes in Cfb (c). Hippocampal Cfb (d) was significantly increased in fructose-fed animals without changes in expression of C4b (b). Data shown are mean ± SEM, normalized to chow-fed animals; asterisks indicate a main effect at p < 0.05.
