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. 2022 Jun 30;13:926220. doi: 10.3389/fimmu.2022.926220

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Copyright © 2022 Muralidharan, Torta, Lin, Olona, Bagnati, Moreno-Moral, Ko, Ji, Burla, Wenk, Rodrigues, Petretto and Behmoaras

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Resolution phase lipids show high inter-individual variability. (A) The coefficient of variation (CV%) was calculated for each lipid for untreated hMDMs. The CV% of technical quality controls (TQC) is shown as grey circles. Dashed line represents 100% CV; Macrophages derived from N=11 donors. (B) The CV% values were calculated for each lipid class and are color coded. The first column (TQC) indicates the technical variation for each lipid class. PC, phosphatidylcholines; PE, phosphatidylethanolamines; PI, phosphatidylinositol; PG, phosphatidylglycerols; PS, phosphatidylserine; LPC, lysophosphatidylcholine; Cer, ceramides; SM, sphingomyelins; HexCer, monohexosylceramides; Hex2Cer, dihexosylceramides; CE, cholesteryl esters; SPB, sphingoid bases; Gb3, globotriaosylceramide; Gb4, globotetraosylceramide.