Table 1. List of the Contents and Sizes of All Simulation Systems.

structure source	solution	replicates	box size (Å)	system notes
2KF8	∼150 mM KCl	3 × 1 μs	50	telomeric two-tetrad GQ (Figure 1)
2KF8	∼150 mM NaCl	3 × 1 μs	50	telomeric two-tetrad GQ (Figure 1)
5M1W	∼150 mM KCl	3 × 2 μs	62	isolated G-hairpin (Figure 2)
5M1W	∼150 mM NaCl	3 × 2 μs	62	isolated G-hairpin (Figure 2)
SC11 snapshot	∼150 mM KCl	1 × 500 ns	72	starting in G-hairpin state 2 (Figure S1)
SC11 snapshot	∼150 mM NaCl	1 × 500 ns	72	starting in G-hairpin state 2 (Figure S1)
SC11 snapshot	∼150 mM KCl	1 × 500 ns	72	starting in the triad/tetrad state (Figure S2)
SC11 snapshot	∼150 mM NaCl	1 × 1 μs	72	starting in the triad/tetrad state (Figure S2)
SC11 snapshot	∼150 mM KCl	2 × 1 μs	62	starting in the unfolded state (Figure S3)