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. 2022 Jun 30;12:861867. doi: 10.3389/fonc.2022.861867

Table 5.

Univariate Cox regression analysis of overall survival according to the conventional stage and the proposed new stage including SUVmax in esophageal squamous cell carcinoma.

Variable Categories Hazard ratio 95% confidence interval p
8th pathological stage I 1.000
II 1.341 0.934–1.926 0.112
III 3.681 2.728–4.968 <0.001
IV 6.687 4.478–9.986 <0.001
Proposed new stage
(SUVmax, median cutoff)
I (I with low SUVmax + II with low SUVmax) 1.000
II (I with high SUVmax + II with high SUVmax + III with low SUVmax) 2.010 1.422–2.840 <0.001
III (III with high SUVmax) 4.805 3.517–6.564 <0.001
IV 7.837 5.220–11.767 <0.001
Proposed new stage (SUVmax, best cutoff) I (I with low SUVmax + II with low SUVmax) 1.000
II (I with high SUVmax + II with high SUVmax + III with low SUVmax) 2.250 1.544–3.279 <0.001
III (III with high SUVmax) 5.474 3.806–7.872 <0.001
IV 9.473 6.048–14.839 <0.001