Table 7.

The number of trials by economic assessment, intervention, measured animal outcomes, and outcome utilization and reporting

Economic assessment (Citations)	Intervention	All animal outcomes measured	Animal outcomes utilized2	Primary?3	N
Break-even analysis1 (n = 3)
(Peterson et al., 1989; Lewis et al., 1990)	Feeding (n = 2)	Carcass, Live perf.	All	-	1
		Live perf.	All	-	1
	Management (n = 1)	Live perf.	All	-	1
Cost–benefit analysis1 (n = 8)
(Kadel et al., 1985; Bechtol et al., 1991; Soll et al., 1991; Xiong et al., 1991; Blaine and Nsahlai, 2011; Van Donkersgoed et al., 2013; Van Donkersgoed and Hendrick, 2013)	Feeding (n = 1)	Carcass, Live perf.	Some	NR	1
	Management (n = 2)	Carcass, Live perf.	Some	NR	1
		Health, Live perf.	Some	NR	1
	Parasite control (n = 1)	Carcass	All	-	1
	Parenteral antimicrobial (n = 2)	Health	None	-	2
	Vaccination (n = 2)	Health	All	-	2
Cost-effectiveness/Relative cost-effectiveness1 (n = 25)
(Bauck et al., 1989; Jim et al., 1999; Guichon et al., 2000; Schunicht et al., 2000; Schunicht et al., 2002a; Schunicht et al., 2002b; Schunicht et al., 2003; Booker et al., 2006; Booker et al., 2007; Schunicht et al., 2007;Perrett et al., 2008a; Perrett et al., 2008b; Perrett et al., 2008c; Van Donkersgoed et al., 2008a; Van Donkersgoed et al., 2008b; Wildman et al., 2008; Hannon et al., 2009; Wildman et al.,2009; Abutarbush et al., 2012; Van Donkersgoed and Merrill, 2012; Van Donkersgoed and Merrill, 2013a; Van Donkersgoed and Merrill, 2013b; Tennant et al., 2014; Van Donkersgoed et al., 2017)	Feeding (n = 1)	Carcass, Health, Live perf.	Significant only	NR	1
	Parasite control (n = 3)	Carcass, Health, Live perf.	Significant only	NR	1
		Health, Live perf.	Some	Yes	1
		Live perf.	All	-	1
	Parenteral antimicrobial (n = 17)	Carcass, Health, Live perf.	All	-	1
			Significant only	No	1
				NR	2
				Yes	3
		Health	Significant only	NR	1
				Yes	1
		Health, Live perf.	Significant only	No	1
				NR	1
				Yes	6
	Vaccination (n = 4)	Carcass, Health, Live perf.	Significant only	NR	4
Decision analysis1(n = 1)
(Booker et al., 1992)	Parenteral antimicrobial (n = 1)	Health	All	-	1
Economic advantage1 (n = 1)
(Edwards and Laudert, 1984)	Management (n = 1)	Carcass, Health, Live perf.	Some	NR	1
Enterprise analysis (n = 14)
(Hinman et al., 1999; Sawyer et al., 2004; Anderson et al., 2005; DeRouen and Foster, 2006; Bedwell et al., 2008; Kirkpatrick et al., 2008; McCartney et al., 2008; Mulliniks et al., 2012; Parish et al., 2013; Şentürklü et al., 2018)	Feeding (n = 9)	Carcass, Health	Some	NR	3
		Carcass, Live perf.	All	-	2
		Carcass, Live perf.	Some	NR	1
		Carcass, Health, Live perf.	All	-	3
	Management (n = 3)	Carcass, Live perf.	All	-	3
	Multiple (n = 1)	Carcass, Health, Live perf.	All	-	1
	Vaccination (n = 1)	Carcass, Health, Live perf.	Some	NR	1
Gross Margin analysis (n = 1)
(Lefebvre et al., 2006)	Multiple (n = 1)	Carcass, Live perf.	Some	NR	1
Not Enough Information (n = 5)
(Williams et al., 1991; Loerch and Fluharty, 1998; Flatt et al., 2003; MacGregor and Wray, 2004; Mir et al., 2008)	Feeding (n = 3)	Carcass	Some	Yes	1
		Carcass, Live perf.	Some	NR	1
		Carcass, Health, Live perf.	Some	NR	1
	Parasite Control (n = 1)	Health, Live Perf.	Not reported	-	1
	Vaccination (n = 1)	Carcass, Health, Liveperf.	Some	NR	1
Partial Budget (n = 52)
(Flack et al., 1967; Alexander and Miller, 1972; Price et al., 1978; Leland et al., 1980; Wellington and Van Schalkwyk, 1982; Campbell et al., 1987; Grimson et al., 1987; Karren et al., 1987; Louis et al., 1988; Mechor et al., 1988; Stanton et al., 1989; Jim et al., 1992; Bartle et al., 1994; Gallo and Berg, 1995; Dubeski et al., 1997; Jim et al., 1999; Gummow and Mapham 2000; MacGregor et al., 2001; Macken et al., 2003;Sawyer et al., 2003;Berthiaume, 2006;Stalker et al., 2006;McEwen et al., 2007; Shike et al., 2007; Vázquez-Añón et al., 2007; Bryant et al., 2008; Elam et al., 2008; Step et al., 2008;Larson et al., 2009;Sides et al., 2009; Cooprider et al., 2011; Van Donkersgoed et al., 2011; Swyers et al., 2014; Van Donkersgoed et al., 2014; Kononoff et al., 2015; Rogers et al., 2015; Forte et al., 2018; Rivera et al., 2018)	Feeding (n = 16)	Live perf.	None	-	1
		Carcass, Live perf.	All	-	3
			Some	NR	2
			Significant only	NR	1
			Not reported	-	1
		Health, Live perf.	All	-	1
			Some	-	2
		Carcass, Health, Live perf.	Some	NR	4
			Significant only	NR	1
	Management (n = 9)	Carcass, Live perf.	All	-	2
			Some	NR	2
		Carcass, Health, Live perf.	All	-	1
			Some	NR	2
		Health, Live perf.	All	-	2
	Multiple (n = 6)	Carcass, Live perf.	All	-	3
			Some	NR	3
	Parasite Control (n = 16)	Carcass, Health	Some	NR	1
		Carcass, Health, Live perf.	Some	Yes	1
			Significant only	NR	1
		Health, Live perf.	All	-	6
		Live perf.	All	-	7
	Parenteral antimicrobial (n = 2)	Health	Some	Yes	2
	Vaccination (n = 3)	Carcass, Health	All	-	1
		Carcass, Health, Live perf.	All	-	1
			Some	NR	1
Profitability1 (n = 3)
(Stegner et al., 2013; Gillespie-Lewis et al., 2016)	Feeding (n = 2)	Carcass, Live perf.	All	-	2
	Parenteral antimicrobial (n = 1)	Carcass, Health, Live perf.	Not reported	-	1

Live perf. = Live performance; NR = Not reported.

Includes only author reported types of economic assessment.

Which of the measured animal outcomes were used to derive the cost/benefit of the intervention.

If the animal outcomes used to determine the cost/benefit of the intervention were included in the authors’ stated primary objectives. Only “significant only” or “some” animal outcome utilized were extracted. If the authors did not report their primary objective(s), it was extracted as “not reported.”