Figure 3. Results From Models of Effect of Group (Patient vs Control) on Brain-wide Activation by Tissue Type and Distance From Lesion (X Axes) for the Naming Task and for the Semantic Decision Task.

The y axis shows estimate of the effect of group status () and 95% CI. An asterisk indicates a significant difference between patients and controls (p < 0.01). The discontinuity in the x axes indicates that the rightmost data points included all voxels beyond the perilesional shell. Results are shown for language cortex (A, B), language-capable cortex (C, D), and nonlanguage cortex (E, F). For the naming task, patient activation was reduced in language and language-capable tissue up to 12 mm from the lesion boundary and up to 4 mm for nonlanguage tissue. For the semantic decision task, activation was reduced in language and language-capable tissue up to 8 mm from the lesion boundary.