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. 2022 Jul 14;20:323. doi: 10.1186/s12951-022-01536-0

Fig. 6.

Fig. 6

Effects on osteolysis, joint cartilage and inflammation in vivo after RA mice injected with NPs. a μCT results of ankle joint in RA mice injected with NPs for 4 weeks. b HE and safranin O/ fast green (SO/FG) staining of ankle joint in RA mice injected with NPs for 4 weeks. c Inflammatory IL-17 staining of spleen (sp) and ankle joint (an) in RA mice injected with NPs for 4 weeks. ** indicated the significant difference of p ≤ 0.05 compared with Vehicle, # indicated the significant difference of p ≤ 0.05 compared with Ctrl