Table 3.
Stress measures | Probe | Coefd | p Valuee | FDRf | Chrg | Illumina gene annotation |
---|---|---|---|---|---|---|
PSSa | cg09723184 | 0.03 | 6.23E-06 | 0.87 | chr8 | FBXO43 |
cg27293447 | −0.04 | 7.25E-06 | 0.87 | chr2 | LOC102800447 | |
PDQb | cg03756940 | −0.05 | 1.10E-07 | 0.08 | chr2 | NA |
cg00008621 | −0.04 | 2.06E-07 | 0.08 | chr14 | HIF1A | |
Cortisol | cg18197866 | 0.003 | 2.55E-07 | 0.16 | chr12 | PXN |
cg20460797 | −0.006 | 4.17E-07 | 0.16 | chr4 | NSG1 | |
FSIc | cg24715106 | 0.54 | 2.51E-07 | 0.2 | chr11 | AQP11 |
cg23782719 | −0.42 | 2.54E-06 | 0.56 | chr6 | RNF182 |
The table shows top two CpGs from the EWAS of the interaction analysis that are associated with the stress measures
NA Not available
aCohen Perceived Stress Scale
bPrenatal Distress Questionnaire
cFetal Stress Index
dRegression coefficients from the statistical model
eSignificance from the statistical model
fFalse discovery rate
gChromosome