Table 2.
Overlapping KEGG pathways between the two groups
| KEGG Pathways | Common Genes | CIA/Control | BZXD/CIA | ||
|---|---|---|---|---|---|
| PValue | Count | PValue | Count | ||
| 28 Day | |||||
| Focal adhesion | MYLPF, ACTN3, CAV1, COL5A2, COL6A1, CHAD, TLN2 | 0.0011 | 11 | 0.0000 | 39 |
| Carbon metabolism | HK3, PC, ME1, PGP, ENO2 | 0.0021 | 8 | 0.0000 | 33 |
| Biosynthesis of antibiotics | ENO2 | 0.0051 | 10 | 0.0000 | 40 |
| ECM-receptor interaction | COL5A2, COL6A1, CHAD | 0.0102 | 6 | 0.0000 | 24 |
| Glycolysis / Gluconeogenesis | HK3, ALDH2, ENO2 | 0.0199 | 5 | 0.0000 | 14 |
| Pyruvate metabolism | PC, ALDH2, ME1 | 0.0211 | 4 | 0.0000 | 12 |
| Complement and coagulation cascades | CFD, KLKB1, KNG2, KNG1, C2 | 0.0007 | 7 | 0.0000 | 18 |
| Metabolic pathways | HIBADH, GDA, HEXB, PYGM, NT5C2, ENO2, PAPSS1, HK3, ALDH2, ME1, GGT5, CKM, ACLY, PC, FASN, PGP, PLPP3 | 0.0113 | 30 | 0.0000 | 96 |
| 42 Day | |||||
| Focal adhesion | MYLPF, COL3A1, ACTN3, COL6A5 | 0.0012 | 12 | 0.0139 | 6 |
| Carbon metabolism | RPIA, PHGDH, GPT | 0.0003 | 10 | 0.0092 | 5 |
| Biosynthesis of antibiotics | RPIA, PHGDH | 0.0053 | 11 | 0.0620 | 5 |
| Fatty acid metabolism | FASN, ACADSB | 0.0149 | 5 | 0.0524 | 3 |
| Metabolic pathways | AHCYL1, GPT, AKR1B8, PAPSS1, ALAD, UROD, PHGDH, FDPS, ACADSB, RPIA, FASN | 0.0046 | 36 | 0.0098 | 17 |