Table 2 |.
Results for 51 proteins with experimental cryo-EM density maps
| MDFF | Rosetta | MAINMAST | DEMo-EM | |
|---|---|---|---|---|
| TM-score | 0.55 (0.24) | 0.47 (0.28) | 0.36 (0.24) | 0.88 (0.09) |
| RMSD (Å) | 17.7 (11.0) | 24.1 (16.6) | 23.0 (10.3) | 4.2 (3.2) |
| TM-score (domain)a | 0.56 (0.21) | 0.47 (0.26) | 0.42 (0.32) | 0.84 (0.13) |
| RMSD (domain) (Å)b | 7.2 (4.2) | 11.4 (10.0) | 12.0 (8.1) | 3.2 (2.8) |
| Rama favoured (%)c | 72.0 (7.4) | 88.1 (5.2) | 47.4 (28.8) | 86.1 (5.9) |
| Rotamer outliers (%) | 8.6 (3.3) | 0.5 (0.4) | 20.3 (21.4) | 3.9 (2.2) |
| Clash score | 3.9 (4.0) | 9.8 (7.1) | 821.5 (1,137.3) | 2.1 (0.2) |
| MolProbity score | 2.49 (0.41) | 2.02 (0.36) | 4.74 (0.68) | 1.66 (0.55) |
| EMringer score | 0.33 (0.31) | 1.08 (0.78) | 0.79 (0.69) | 1.45 (0.95) |
| iFSC | 0.30 (0.15) | 0.37 (0.20) | 0.35 (0.17) | 0.55 (0.23) |
Values presented as average (s.d.), with the best results in each category in bold.
a
TM-score of individual domain models in full-length models.
b
rMSD of individual domains models in full-length models.
c
percentage of ‘ramachandran favoured’ residues.