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. 2022 Jul 14;181(9):3501–3509. doi: 10.1007/s00431-022-04561-1

Table 4.

Influence of the severity of COVID-19 on the development of long-COVID symptoms in the whole study group and within the individual cohorts of immunocompromised and immunocompetent children

Severity of COVID-19 and the prevalence of long-COVID < 12-week post-infection
Asymptomatic Mild Moderate Severe p
Whole study group 8 (19.1%) 30 (46.9%) 22 (68.8%) 7 (77.8%)  < 0.01
  ID ( +) 5 (15.6%) 12 (44.4%) 5 (62.5%) 2 (66.7%) 0.01
  ID (-) 3 (30.0%) 18 (48.7%) 17 (70.9%) 5 (83.3%) 0.02
Severity of COVID-19 and the prevalence of long-COVID > 12-week post-infection
Asymptomatic Mild Moderate Severe p
Whole study group 3 (7.1%) 10 (15.6%) 13 (40.6%) 6 (66.7%)  < 0.01
  ID ( +) 2 (6.25%) 2 (7.4%) 3 (37.5%) 2 (66.7%) 0.02
  ID (-) 1 (10.0%) 8 (21.6%) 10 (41.7%) 4 (66.7% 0.01

ID ( +), children with immunodeficiency; ID (-), children without immunodeficiency