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. 2022 Jul 14;9(1):92. doi: 10.1186/s40537-022-00643-x

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — The immune landscape of GBM. a The immune landscape of GBM. Each dot represents a patient, and different colors represent different immune subtypes. The horizontal axis represents the principal component 1, and the vertical axis represents the principal component 2. b Correlation between principal component 1/2 and 28 immune cell enrichment scores. c Immune landscape of the subgroups of GBM immune subtypes. Differences of 28 immune cells enrichment scores in the subgroups of IS3 (d) and IS4 (e). Immune landscape of samples from three extreme locations (f) and their prognostic status (g). ⁻p ≥ 0.1, ^·p < 0.1, *p < 0.05, **p < 0.01, ***p < 0.001