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. Author manuscript; available in PMC: 2023 May 1.
Published in final edited form as: Comput Toxicol. 2022 Mar 17;22:100223. doi: 10.1016/j.comtox.2022.100223

Table 6.

Summary of databases including data associated with neurotoxicity and developmental neurotoxicity (non-exhaustive list).

Database Description Link and reference

Alternatives Assessment Dashboard Hazard Database Collection of hazard data compiled for the Alternatives Assessment Dashboard https://catalog.data.gov/dataset/alternatives-assessment-dashboard-hazard-database-version-1-0-generated-12-07-2018
BindingDB Binding Database https://www.bindingdb.org/
ChemBL/PubChem Database of bioactive drug-like small molecules https://www.ebi.ac.uk/chembl/
DNT-DIVER Developmental NeuroToxicity Data Integration and Visualization Enabling Resource https://sandbox.ntp.niehs.nih.gov/neurotox/
eChemPortal The Global Portal to Information on Chemical
Substances
https://www.echemportal.org/echemportal/
ExCAPE-DB Exascale Compound Activity Prediction Engine Database https://solr.ideaconsult.net/search/excape/
HSDB Hazardous Substances Data Bank https://www.nlm.nih.gov/databases/download/hsdb.html
OpenFoodTox European Food Safety Authority chemical hazards database https://data.europa.eu/euodp/en/data/dataset/openfoodtox-efsa-s-chemical-hazards-database
PDSP Ki database The NIMH Psychoactive Drug Screening Program
(PDSP) Ki database
https://pdsp.unc.edu/databases/kidb.php
RTECS Registry of Toxic Effects of Chemical Substances (National Institute for Occupational Safety and Health (NIOSH)) https://www.cdc.gov/niosh/rtecs/default.html
SIDER Side Effect Resource database http://sideeffects.embl.de/
ToxCast/Tox21 Chemical screening data from the ToxCast project and Tox21 collaboration https://www.epa.gov/chemical-research/exploring-toxcast-data-downloadable-data
ToxRefDB The Toxicity Reference Database developed by the U.S. Environmental Protection Agency https://github.com/USEPA/CompTox-ToxRefDB