Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Mar 22;46(8):1036–1047. doi: 10.1097/PAS.0000000000001889

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

PMC Copyright notice

Histologic features of diffuse SARS-CoV-2 placentitis (case 1) with confirmation by IHC staining for SARS-CoV-2 spike protein. A, Extensive villous agglutination with ScT necrosis, perivillous fibrin (left), and chronic intervillositis (right) (hematoxylin and eosin). B, Strong positive staining for SARS-CoV-2 capsid protein involving nearly all ScT within areas of villous agglutination (SARS-CoV-2 immunostain). C, Extensive perivillous fibrin and ScT necrosis; manifesting features intermediate between non–COVID-related villous infarction and MPVF (hematoxylin and eosin). D, ScT nuclei with features suggestive of apoptosis: nuclear condensation, membrane blebbing, and cell shrinkage (hematoxylin and eosin).