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. Author manuscript; available in PMC: 2022 Jul 14.
Published in final edited form as: J Adolesc Health. 2021 Jul 18;69(6):957–963. doi: 10.1016/j.jadohealth.2021.05.014

Table 1.

Major parameters used in the cost-effectiveness analyses

Parameters Value Range Reference
Probability of background testing
 Male, among those tested positive .50 .20–.50 Authors’ assumption that only male students with symptomatic infections would get tested, 50% probability of symptomatic infection [22]
 Female, among those who were sexually active .44 .22–.66 Center for Disease Control and Prevention Medicaid study of 2012 Michigan Medicaid data (personal communication)
 Female, among those tested positive .55 .276–.728 Authors’ calculation based on 20% probability of symptomatic infection [22], all symptomatically infected females would get tested, 44% of asymptomatically infected females would get tested
Test sensitivity .95 .9–1 [17]
Treatment efficacy (azithromycin) .92 .8–1 [17]
Probability of reinfection
 Male .11 .065–.178 [19]
 Female .18 .09—.27 [18]
Probability of natural clearance
 Male .20 .10–.30 [20]
 Female .20 .10–.30 [20]
Probability of developing epididymitis or PID
 Epididymitis .02 .01–.05 [22]
 PID .16 .12–.30 .16 (ranging from .12 to .17; [25]), .30 ([24]; [7]), and .15 ([17,22])
Transmission probability per partnership
 Male to female .70 .25–.80 [21]
 Female to male .68 .25–.80 [21]
Clinical screening/testing and treatment costs
 Screening/testing ($) 57.50 28.7–86.2 [17]
 Treatment ($) 29.80 14.9–44.7 [24]
Treatment costs of sequelae
 Epididymitis ($) 1,347 673–2,020 [17]
 PID ($) 3,513 1,756–5,269 [26]
QALYs lost/case
 Epididymitis .01 .0048–.01 [27]
 PID .34 .177–.53 [27]

PID = pelvic inflammatory disease; QALY = quality-adjusted life-years.