BRAF
|
7q |
Serine/threonine kinase that functions in MAP kinase/ERK signaling pathway |
GNAS
|
20q |
Guanine nucleotide-binding protein functions in adenylyl cyclase activation |
KLF4
|
9q |
A Kruppel family transcription factor with a number of functions, including p53 mediated DNA damage repair |
KRAS
|
12p |
Member of the small GTPase family |
PIK3CA
|
3q |
This phosphoinositide-3-kinase participates in cellular signaling by phosphorylating downstream targets |
P16/CDKN2A
|
9p |
Cell cycle control |
RNF43
|
17q |
A RING-type E3 ubiquitin ligase that functions in Wnt signaling |
SMAD4
|
18q |
Transforming growth factor—beta signaling |
TGFBR2
|
3p |
Transforming growth factor—beta signaling |
TP53
|
17p |
Induces cell cycle arrest, apoptosis and other changes in response to cellular stresses |