Table 5.
Covariates and their coefficients selected by least absolute shrinkage and selection operator regression on five versions of the datasets with imputed data
| Imputed dataset | |||||
|---|---|---|---|---|---|
| Covariate | 1 | 2 | 3 | 4 | 5 |
| (Intercept) | – 4.70E+00 | – 4.78E+00 | – 4.39E+00 | – 4.77E+00 | – 5.51E+00 |
| Age | 1.62E–02 | 1.90E–02 | 1.43E–02 | 1.89E–02 | 2.74E–02 |
| Age:BUN | 1.94E–04 | ||||
| Age:Ferritin | 2.99E–07 | ||||
| Age:Mechanical_Ventilation | 1.19E–02 | ||||
| Age:Remdesivir | 1.14E–03 | ||||
| BUN | 1.39E–02 | 1.36E–02 | 1.26E–02 | 1.35E–02 | 1.45E–02 |
| CAD | 5.77E–02 | ||||
| CAD:AST | 7.32E–05 | ||||
| CAD:BUN | 1.10E–03 | ||||
| COPD:BUN | 1.47E–03 | ||||
| COPD:Mechanical_Ventilation | 1.42E–01 | ||||
| CRP | 8.50E–05 | ||||
| CRP:BUN | 6.12E–06 | ||||
| Ddimer | 1.29E–02 | 3.97E–03 | 4.67E–03 | 6.57E–03 | 2.84E–02 |
| Ferritin | 1.56E–05 | 1.03E–05 | 7.56E–06 | 1.23E–05 | 2.10E–05 |
| Gender:Dimer | 1.12E–02 | ||||
| Gender:Mechanical_Ventilation | 2.02E–01 | ||||
| Heart Failure | 1.73E–01 | 1.01E–01 | 2.47E–02 | 1.03E–01 | 2.35E–01 |
| Heart_Failure:BUN | 6.76E–04 | ||||
| Heart_Failure:CRP | 1.06E–03 | ||||
| Heart_Failure:Dimer | 1.21E–02 | ||||
| Mechanical_Ventilation | 2.09E+00 | 2.53E+00 | 2.46E+00 | 2.52E+00 | 2.63E+00 |
| Ondansetron | – 7.97E–02 | – 1.95E–01 | |||
| Ondansetron:Mechanical_Ventilation | – 8.09E–02 | ||||
| Remdesivir | 3.87E–03 | ||||
Covariates are listed alphabetically. All covariates are significant
Age approximate age of patient (one of 35, 45,…, 75 years), AST aspartate transaminase level, BUN blood urea nitrogen, CAD coronary artery disease, COPD chronic obstructive pulmonary disease, CRP C-reactive protein, : indicates interaction between two covariates
Negative sign means association with decreased mortality (bold)