ChiCTR‐TCS‐14005054.

Study name	Cilostazol in decreasing progression of cerebral white matter hyperintensities (DREAM)
Methods	Parallel double‐blind randomised trial
Participants	140 men and women aged 65–85 years
Interventions	Cilostazol Placebo
Outcomes	Primary outcome Change of WMH volume on MRI between baseline and end of study Secondary outcomes Change in other brain measures in MRI (lacunes, microbleeds, brain volumes (cortical grey matter, white matter, ventricular and sulcal CSF) and Diffusing tensor imaging measures (mean fractional anisotropy of WMH, normal appearing white matter, grey matter) or Clinical measures (Montreal Cognitive Assessment, 30‐minute battery of the NINDS‐CSN VCI Neuropsychology Protocols, NPI, Instrumental Activities of Daily Living, gait and balance, incident clinical events (e.g. stroke, dementia)
Starting date	27 October 2014
Contact information	Name: Prof Vincent Chung Tong Mok Address: Rm 124010, 10/F, Clinical Sciences Building, Prince of Wales Hospital, Shatin, N.T. Hong Kong Contact number: +852 2632 2195 Contact email: vctmok@cuhk.edu.hk
Notes	CUHK_CCT00430; ChiCTR‐TCS‐14005054 www2.ccrb.cuhk.edu.hk/registry/public/269