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. 2022 Jul 1;6(8):bvac095. doi: 10.1210/jendso/bvac095

Table 2.

Physical and metabolic characteristics before and after weight loss and aerobic exercise

WL (n = 21) AEX (n = 20)
Pre Post Pre Post
Age, y 60 ± 1 62 ± 2
Body weight, kg 102.9 ± 3.9 93.7 ± 3.5g,a 92.7 ± 3.6 91.5 ± 4.1
BMI 36 ± 1 33 ± 1c,a 32 ± 1 32 ± 1
VO2max, L/min 2.3 ± 0.1 2.3 ± 0.1a 2.4 ± 0.1 2.7 ± 0.1g
VO2max, mL/kg/min 23.0 ± 1.2 24.6 ± 1.3e,a 25.1 ± 1.1 29.2 ± 1.3e
VO2max, mL/kgFFM/min 40.0 ± 1.0 40.0 ± 1.1 41.7 ± 1.47 44.4 ± 3.0
% Body fat 44.2 ± 1.7 41.2 ± 2.0g 38.3 ± 1.8 36.9 ± 2.1d
Fat mass, kg 45.7 ± 2.5 38.9 ± 2.4g,a 36.3 ± 2.5 35.0 ± 2.9
FFM, kg 57.4 ± 2.8 55.9 ± 2.7g,a 57.6 ± 2.4 58.4 ± 2.6c
Fasting glucose, mg/dL 101 ± 3 92 ± 2g,b 96 ± 2 95 ± 2
120-min glucose, mg/dL 150 ± 10 128 ± 9e 131 ± 9 127 ± 9
Fasting insulin, pmol/L 109 ± 11 85 ± 8f 100 ± 9 90 ± 9a
120-min insulin, pmol/L 685 ± 93 472 ± 57f 595 ± 92 505 ± 56
M, μmol.kg–1.min–1 22.1 ± 2.9 31.2 ± 2.8e 31.7 ± 2.6 37.3 ± 2.8c
M, μmol.kgFFM–1.min–1 40.8 ± 4.6 55.2 ± 4.7d 52.2 ± 4.7 59.6 ± 5.1c
HOMA-IR 4.0 ± 0.5 2.8 ± 0.3e 3.4 ± 0.3 3.1 ± 0.3

All participants (n = 41) before and after the AEX (n = 20) and WL (n = 21) intervention. Values are mean ± SEM.

Abbreviations: AEX, aerobic exercise; BMI, body mass index; FFM, fat free mass; HOMA-IR, homeostatic model assessment of insulin resistance; VO2max, maximal oxygen consumption; WL, weight loss.

Statistically significant different pre and post intervention WL vs AEX:

a P < .001;

b P < .05;

c P ≤ .05;

d P < .01;

e P < .001;

f P˂.005; and

g P ≤ .0001.