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. 2021 Mar 26;100(12):e25185. doi: 10.1097/MD.0000000000025185

Table 5.

Results of this analysis.

Endpoints OR with 95% CI P value
TIMI defined major bleeding 2.45 [1.45–4.12] .0008
TIMI defined minor bleeding 3.12 [1.71–5.70] .0002
ISTH major bleeding 2.49 [1.80–3.45] .00001
ISTH defined minor bleeding 2.33 [0.91–5.96] .08
GUSTO defined severe bleeding 3.00 [1.56–5.78] .01
Any bleeding event 1.91 [1.31–2.77] .0007
Fatal bleeding 10.96 [0.61–198.3] .11
All-cause mortality 1.12 [0.89–1.40] .33
MACEs 0.96 [0.82–1.14] .67
Stroke 0.73 [0.44–1.20] .22
Stent thrombosis 0.72 [0.47–1.12] .15
MI 0.92 [0.75–1.13] .44

CI = confidence intervals, GUSTO = global use of strategies to open occluded arteries, ISTH = International society on thrombosis and hemostasis, MACEs = major adverse cardiac events, MI = myocardial infarction, OR = odds ratios, TIMI = thrombolysis in myocardial infarction.