Table 5.
Results of this analysis.
Endpoints | OR with 95% CI | P value |
TIMI defined major bleeding | 2.45 [1.45–4.12] | .0008 |
TIMI defined minor bleeding | 3.12 [1.71–5.70] | .0002 |
ISTH major bleeding | 2.49 [1.80–3.45] | .00001 |
ISTH defined minor bleeding | 2.33 [0.91–5.96] | .08 |
GUSTO defined severe bleeding | 3.00 [1.56–5.78] | .01 |
Any bleeding event | 1.91 [1.31–2.77] | .0007 |
Fatal bleeding | 10.96 [0.61–198.3] | .11 |
All-cause mortality | 1.12 [0.89–1.40] | .33 |
MACEs | 0.96 [0.82–1.14] | .67 |
Stroke | 0.73 [0.44–1.20] | .22 |
Stent thrombosis | 0.72 [0.47–1.12] | .15 |
MI | 0.92 [0.75–1.13] | .44 |
CI = confidence intervals, GUSTO = global use of strategies to open occluded arteries, ISTH = International society on thrombosis and hemostasis, MACEs = major adverse cardiac events, MI = myocardial infarction, OR = odds ratios, TIMI = thrombolysis in myocardial infarction.