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. 2022 May 17;107(8):2216–2227. doi: 10.1210/clinem/dgac303

Table 1.

Baseline characteristics of participantsa

Dietary group
MD (n = 84) TJD (n = 85) CD (n = 84)
Male, no. (%) 71 (84) 72 (85) 73 (87)
Age, y 38 ± 8 37 ± 9 38 ± 9
Education, no. (%)
 0-12 y 4 (5) 8 (9) 4 (5)
 ≥13 y 80 (95) 77 (91) 80 (95)
Current smoker, no. (%) 16 (19) 11 (13) 20 (24)
Alcohol drinker, no. (%) 67 (80) 58 (68) 61 (73)
Medications, no. (%)
 Lipid-lowering drugs 1 (1.2) 0 (0) 1 (1.2)
 Antihypertensive drugs 9 (11) 15 (18) 11 (13)
Physical activity, no. (%)b
 High 9 (11) 16 (19) 14 (21)
 Moderate 60 (72) 47 (56) 55 (21)
 Low 14 (17) 21 (25) 15 (21)
Dietary intakec
 Energy, male, kcal/d 1973 ± 410 1996 ± 513 2003 ± 484
 Energy, female, kcal/d 1893 ± 412 1785 ± 276 1538 ± 378
 Total fat (%) 33.9 ± 6.4 33.0 ± 6.5 33.8 ± 7.6
 Carbohydrate (%) 49.7 ± 7.2 49.7 ± 7.2 48.7 ± 8.6
 Protein (%) 16.8 ± 2.2 17.3 ± 2.7 17.5 ± 2.7
 Cholesterol, mg/d 456 ± 180 498 ± 216 524 ± 258
 Fiber, g/d 9.0 ± 3.8 9.2 ± 3.7 8.5 ± 3.0
Anthropometrics and MRId
 Weight, kg 78.9 ± 12.5 79.7 ± 10.9 79.5 ± 12.3
 BMI, kg/m2 26.6 ± 3.2 26.8 ± 3.0 26.7 ± 3.0
 SBP, mmHg 129 ± 13.3 130 ± 16.6 126 ± 12.6
 DBP, mmHg 85.8 ± 10.0 85.9 ± 11.6 84.1 ± 10.4
Abdominal fat, cm2e 261 (126) 273 (102) 270 (109)
 VAT, cm2e 86.7 (53.4) 95.4 (57.5) 82.6 (77.6)
 SAT, cm2e 172 (90.0) 187 (96.1) 176 (74.1)
OGTT
 0-h glucose, mmol/Le 6.13 (0.81) 6.03 (0.60) 5.97 (0.63)
 AUC glucose, mmol*h/Le 16.4 (5.52) 17.0 (4.16) 17.2 (4.74)
 Matsuda Index 13.1 ± 7.0 11.7 ± 6.4 12.0 ± 6.5
CGMf
 Mean glucose, mmol/Le 5.90 (0.81) 5.85 (0.60) 5.99 (0.80)
 TBR, %e 1.49 (3.98) 1.07 (3.67) 1.04 (3.79)
 TAR, %e 0.21 (1.48) 0.42 (1.26) 0.52 (1.67)
 Nighttime SD, mmol/L 0.65 ± 0.27 0.59 ± 0.25 0.61 ± 0.23

No significant between-group difference was observed among all characteristics above.

Abbreviations: AUC, area under the curve; CD, control diet; CGM, continuous glucose monitoring; DBP, diastolic blood pressure; MD, Mediterranean diet; OGTT, oral glucose tolerance test; SAT, subcutaneous adipose tissue; SBP, systolic blood pressure; SD, standard deviation; TAR, time above range (> 10.0 mmol/L); TBR, time below range (< 3.9 mmol/L); TJD, traditional Jiangnan diet; VAT, visceral adipose tissue.

a Data are mean ± standard deviation or n (%) unless otherwise stated.

b Physical activity was calculated based on the International Physical Activity Questionnaire.

c Dietary intake data were calculated from the 3-day dietary record.

d A total of 183 participants had valid magnetic resonance imaging records at baseline, 54 in Mediterranean group, 65 in traditional Jiangnan group, and 64 in control group.

e Data are medians (interquartile range).

f 200 participants had valid CGM records at baseline, 63 in Mediterranean group, 68 in traditional Jiangnan group, and 69 in control group.