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. 2022 Mar 19;107(8):2350–2361. doi: 10.1210/clinem/dgac165

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© The Author(s) 2022. Published by Oxford University Press on behalf of the Endocrine Society.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — Discovery cohort: association of imputed single-nucleotide variations (SNVs) with follicle-stimulating hormone (FSH) levels. Manhattan plot of imputed genome-wide association study data depicts SNVs associated with FSH. X axis: genomic coordinates of tested SNVs on respective chromosomes. Y axis: significance level on a –log₁₀ scale. The suggestive significance threshold is indicated by the gray horizontal line (P = 8.56e-6). The genome-significance threshold is indicated by the black horizontal line (P = 4.28e-7).