Table 4.
AUC and 95% CIs for 2-y ROC curves for FPIR and OGTT-derived measures across studies
| TN-07 | DPT-1 | |||
|---|---|---|---|---|
| AUC | (95% CI) | AUC | (95% CI) | |
| FPIR | 0.707 | (0.602-0.812) | 0.628 | (0.537-0.719) |
| C-Peptide AUC | 0.611 | (0.479-0.742) | 0.538 | (0.432-0.643) |
| C-Peptide Index | 0.717 | (0.621-0.813) | 0.721 | (0.638-0.803) |
| C-Peptide 30-0 min | 0.648 | (0.546-0.751) | 0.626 | (0.532-0.721) |
| Index60 | 0.778 | (0.698-0.858) | 0.763 | (0.677-0.848) |
Abbreviations: AUC, area under the curve; DPT-1, Diabetes Prevention Trial-Type 1 Diabetes; FPIR, first-phase insulin response; OGTT, oral glucose tolerance test; TN-07, Type 1 Diabetes TrialNet “Oral Insulin for Prevention of Diabetes in Relatives at Risk for T1D.”