Table 5.
Adjusted P values comparing FPIR 2-y AUC vs OGTT-derived measures 2-y AUC across studies
| TN-07a | DPT-1a | |
|---|---|---|
| FPIR vs | ||
| Index60 | 0.3493 | 0.0120 |
| C-Peptide Index | 0.8403 | 0.1402 |
| C-peptide AUC | 0.3380 | 0.1483 |
| C-Peptide 30-0 min | 0.3493 | 0.9731 |
Abbreviations: AUC, area under the curve; DPT-1, Diabetes Prevention Trial-Type 1 Diabetes; FPIR, first-phase insulin response; OGTT, oral glucose tolerance test; TN-07, Type 1 Diabetes TrialNet “Oral Insulin for Prevention of Diabetes in Relatives at Risk for T1D.”
a Adjusted P values using the Benjamini-Hochberg method to control for false-discovery rates.