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. 2022 Apr 21;46(6):e116–e185. doi: 10.1093/jat/bkac023

Table II.

Summary of SC Receptor Agonists’ Toxicity Profiles

Organ system Symptoms and signs
CNS Agitation, psychosis, irritability, seizures, sedation, coma, delirium, hallucinations, paranoia, anxiety, hypo/hyperreflexia and psychomotor impairment
Cardiovascular Tachycardia, hypertension, acute coronary syndrome, arrhythmia, chest pain and myocardial infarction
Pulmonary Respiratory depression and hypopnea
Other Nausea, vomiting, fevers, mydriasis, blurred vision and acute kidney injury
Postmortem findings Organ edema and congestion