Table 2.

PIPs from Bayesian kernel machine regression models^a of chemical mixtures and total body less head aBMD Z-scores in 12- to 19-year-old males (n = 453) and females (n = 395), 2011-2016 NHANES

	Biomarker groups	Group PIP	Individual biomarkers	Individual PIP
Males	Serum PFAS	0.65	PFOA	0.76
			PFOS	0.12
			PFDA	0.03
			PFHxS	0.06
			PFNA	0.03
	High-molecular-weight urinary phthalate biomarkers	0.79	∑DEHPb	0.65
			MBzP	0.22
			MCOP	0.02
			MCNP	0.06
			MCPP	0.05
	Low-molecular-weight urinary phthalate biomarkers	0.77	MBP	0.39
			MiBP	0.58
			MEP	0.03
Females	Serum PFAS	0.33	PFOA	0.26
			PFOS	0.10
			PFDA	0.17
			PFHxS	0.23
			PFNA	0.24
	High-molecular-weight urinary phthalate biomarkers	0.26	∑DEHPb	0.19
			MCOP	0.23
			MCPP	0.23
			MBzP	0.19
			MCNP	0.16
	Low-molecular-weight urinary phthalate biomarkers	0.36	MBP	0.28
			MiBP	0.51
			MEP	0.21

Abbreviations: aBMD, areal bone mineral density; BKMR, Bayesian kernel machine regression; DEHP, di(2-ethylhexyl)phthalate; MBzP, mono-benzyl phthalate; MCNP, mono(carboxynonyl) phthalate; MCOP, mono(carboxyoctyl) phthalate; MCPP, mono-(3-carboxypropyl) phthalate; MEP, mono-ethyl phthalate; MIBP, mono-isobutyl phthalate; NHANES, National Health and Nutrition Examination Survey; PFDA, perfluorodecanoate; PFHxS, perfluorohexane sulfonate; PFNA, perfluorononanoate; PFOA, perfluorooctanoate; PFOS, perfluorooctane sulfonate; MBP, mono-n-butyl phthalate; PIP, posterior inclusion probability.

^aPIPs indicate the relative contribution of individual or group biomarkers to the overall fit of the BKMR model. Models are adjusted for age, race/ethnicity, physical activity, indoor smoking by a household member, urinary creatinine concentrations, NHANES weights, and NHANES cycle.

^bMolar sum of mono (2-ethylhexyl) phthalate, mono(2-ethyl-5-hydroxyhexyl) phthalate, mono(2-ethyl-5-oxohexyl) phthalate, and mono(2-ethyl-5-carboxypentyl) phthalate.