Table 4. Summary of the overall between group effect sizes in RCTs.

Outcome Measures	Sample Size		Effect Size Estimate				Heterogeneity
	K	n	Hedges’ g	95% CI		p	Q		p	I2 (%)
Between Group Differences
Anxiety	12	1269	0.56	[0.35, 0.77]	< 0.01		31.80	< 0.01		65.41
Depression	12	1290	0.43	[0.13, 0.72]	< 0.01		56.42	< 0.01		80.50
CRF	9	1167	0.42	[0.18, 0.66]	< 0.01		38.19	< 0.01		79.05
Follow- Up
Anxiety	5	745	0.58	[0.21, 0.95]	< 0.01		22.20	< 0.01		81.99
Depression	5	911	0.23	[0.15, 0.43]	0.088		37.90	< 0.01		89.45
CRF	5	807	0.33	[0.18, 0.47]	< 0.01		4.28	0.369		6.56

CRF = cancer related fatigue; K = number of studies that were included in the review; n = number of participants; CI = confidence interval.