Table 1. C57BL/6 and CC057 analyte mean and 95% Confidence Interval (CI) at 3 dpi as a function of difference from the uninfected mean.
Analyte (pg/mL) | Mean C57BL/6 difference from uninfected | C57BL/6 95% CI |
Mean CC057 difference from uninfected | CC057 95% CI |
Significance by Mann-Whitney (C57BL/6 versus CC057) |
---|---|---|---|---|---|
CRP | -61,633,583 | [-80,746,132, -42,521,035] | -9,429,167 | [-60,072,281, 41,213,948] | P = 0.0270 |
IFN-α | 2,621 | [587, 4,656] | 283 | [-351, 916] | ns |
E-Selectin | 303,293 | [216,118, 390,467] | -4,646 | [-101,714, 92,422] | P = 0.0257 |
ICAM-1 | 59,309 | [33,804, 84,814] | 12,759 | [-18,375, 43,892] | ns |
Pecam-1 | 132,361 | [76,664, 188,059] | -1,357 | [-56,773, 54,059] | ns |
P-Selectin | 4,667,448 | [-63,667, 9,398,563] | 166,311 | [-874,149, 1,206,772] | P = 0.0098 |
Total PAI-1 | 83,365 | [54,090, 112,640] | 3,236 | [-860, 7,332] | P = 0.0025 |
MMP-9 | 344,725 | [242,434, 447,015] | 9,459 | [-10,451, 29,369] | ns |
Thrombomodulin | 759,107 | [441,391, 1,076,822] | 2,588 | [-14,486, 19,662] | P = 0.0270 |
TNFRI | 23,949 | [11,392, 36,506] | 493 | [-288, 1,274] | P = 0.0172 |
TNFRII | 49,081 | [30,699, 67,464] | 3,476 | [-4,250, 11,203] | P = 0.0172 |
KC | 11,823 | [7,659, 15,987] | 188 | [-12, 388] | P = 0.0012 |
MIG | 12,486 | [8,424, 16,548] | 1,286 | [15, 2,557] | P = 0.0049 |
MCP-1 | 14,664 | [10,604, 18,725] | 511 | [-218, 1,240] | P = 0.0086 |
IP-10 | 5,742 | [3,577, 7,906] | 2,800 | [1,650, 3,950] | P = 0.0392 |
IL-1α | -882 | [-974, -791] | 26 | [-75, 128] | P = 0.0025 |
IL-10 | 75 | [53, 97] | 19 | [6, 32] | P = 0.0098 |
RANTES | 165 | [118, 211] | -1 | [-13, 12] | P = 0.0098 |
IL-6 | 16,131 | [11,722, 20,540] | 46 | [-46, 137] | P = 0.0012 |
TNFα | 256 | [169, 343] | 2 | [-9, 14] | P = 0.0049 |
MIP-1α | 216 | [155, 277] | -16 | [-16, -16] | P = 0.0025 |
MIP-1β | 1,077 | [685, 1,469] | 182 | [-34, 398] | ns |
IFN-γ | 30 | [20, 41] | -1 (undetectable) | [-1, -1] | N/A |
IFN-β | 3,057 | [265, 5,849] | 220 | [52, 388] | P = 0.0049 |
Fractalkine | 1,518 | [897, 2,138] | -24 | [-83, 36] | ns |
MDC | 1,106 | [385, 1,826] | 61 | [-106, 227] | P = 0.0172 |
MIP-3β | 2,694 | [1,881, 3,508] | -19 | [-223, 185] | P = 0.0098 |
Ang2 | 16,248 | [10,387, 22,110] | 649 | [-6,846, 8,144] | P = 0.0159 |
HGF | 49,599 | [36,548, 62,650] | -272 | [-525, -19] | P = 0.0184 |
IL-28B | 482 | [265, 700] | -28 | [-334, 278] | ns |