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. 2022 Jul 14;18(7):e1010649. doi: 10.1371/journal.ppat.1010649

Table 1. C57BL/6 and CC057 analyte mean and 95% Confidence Interval (CI) at 3 dpi as a function of difference from the uninfected mean.

Analyte (pg/mL) Mean C57BL/6 difference from uninfected C57BL/6
95% CI
Mean CC057 difference from uninfected CC057
95% CI
Significance by Mann-Whitney (C57BL/6 versus CC057)
CRP -61,633,583 [-80,746,132, -42,521,035] -9,429,167 [-60,072,281, 41,213,948] P = 0.0270
IFN-α 2,621 [587, 4,656] 283 [-351, 916] ns
E-Selectin 303,293 [216,118, 390,467] -4,646 [-101,714, 92,422] P = 0.0257
ICAM-1 59,309 [33,804, 84,814] 12,759 [-18,375, 43,892] ns
Pecam-1 132,361 [76,664, 188,059] -1,357 [-56,773, 54,059] ns
P-Selectin 4,667,448 [-63,667, 9,398,563] 166,311 [-874,149, 1,206,772] P = 0.0098
Total PAI-1 83,365 [54,090, 112,640] 3,236 [-860, 7,332] P = 0.0025
MMP-9 344,725 [242,434, 447,015] 9,459 [-10,451, 29,369] ns
Thrombomodulin 759,107 [441,391, 1,076,822] 2,588 [-14,486, 19,662] P = 0.0270
TNFRI 23,949 [11,392, 36,506] 493 [-288, 1,274] P = 0.0172
TNFRII 49,081 [30,699, 67,464] 3,476 [-4,250, 11,203] P = 0.0172
KC 11,823 [7,659, 15,987] 188 [-12, 388] P = 0.0012
MIG 12,486 [8,424, 16,548] 1,286 [15, 2,557] P = 0.0049
MCP-1 14,664 [10,604, 18,725] 511 [-218, 1,240] P = 0.0086
IP-10 5,742 [3,577, 7,906] 2,800 [1,650, 3,950] P = 0.0392
IL-1α -882 [-974, -791] 26 [-75, 128] P = 0.0025
IL-10 75 [53, 97] 19 [6, 32] P = 0.0098
RANTES 165 [118, 211] -1 [-13, 12] P = 0.0098
IL-6 16,131 [11,722, 20,540] 46 [-46, 137] P = 0.0012
TNFα 256 [169, 343] 2 [-9, 14] P = 0.0049
MIP-1α 216 [155, 277] -16 [-16, -16] P = 0.0025
MIP-1β 1,077 [685, 1,469] 182 [-34, 398] ns
IFN-γ 30 [20, 41] -1 (undetectable) [-1, -1] N/A
IFN-β 3,057 [265, 5,849] 220 [52, 388] P = 0.0049
Fractalkine 1,518 [897, 2,138] -24 [-83, 36] ns
MDC 1,106 [385, 1,826] 61 [-106, 227] P = 0.0172
MIP-3β 2,694 [1,881, 3,508] -19 [-223, 185] P = 0.0098
Ang2 16,248 [10,387, 22,110] 649 [-6,846, 8,144] P = 0.0159
HGF 49,599 [36,548, 62,650] -272 [-525, -19] P = 0.0184
IL-28B 482 [265, 700] -28 [-334, 278] ns