Table I.

Localization and function of Ca²⁺ channels.

Name	Location	Function
TPC2	Lysosome	Ca2+ release from the lysosome
TRPV1	Plasma membrane	Ca2+ entry from the extracellular space to the cytoplasm
TRPV4	Plasma membrane	Ca2+ entry from the extracellular space to the cytoplasm
TRPM2	Plasma membrane	Ca2+ entry from the extracellular space to the cytoplasm
IP3R1	ER membrane	Ca2+ release from the ER to the cytoplasm
IP3R2	ER membrane	Ca2+ release from the ER to the cytoplasm
VDAC1	Mitochondrial outer membrane	Entry of Ca2+ and other metabolites
Orai	Plasma membrane	Ca2+ entry from the extracellular space to the cytoplasm
P2X7R	Plasma membrane	Ca2+ and Na+ entry from the extracellular space to the cytoplasm, and K+ outflow from the cytoplasm to the extracellular space
KCa3.1	Plasma membrane	Ca2+ entry from the extracellular space to the cytoplasm, and K+ outflow from the cytoplasm to the extracellular space

Ca²⁺, calcium; ER, endoplasmic reticulum; Orai, Orai calcium release-activated calcium modulator; P2X7R, purinergic receptor X7; K⁺, potassium.