Fig. 3.

Summary and comparison of the clinical course of B-cell depleted patients with protracted (a, c) and fast-responding (b, d) COVID-19 pneumonia. Representative CT-scan images and SARS-CoV-2 total Ig levels monitored through the length of hospital stay of two patients. Patient 1 suffered from protracted COVID-19 pneumonia (a, c), while patient 2 had a good response to treatment showing a faster recovery (b, d). A gradual decrease in antibody consumption in our patients receiving multiple CP transfusions was observed that strongly correlated with clinical and radiological improvement. Patient 1 and patient 2 had follicular lymphoma, and multiple myeloma, respectively. Ig immunoglobulin, PCR polymerase chain reaction, CPT convalescent plasma therapy