FIGURE 3.

NR+Caff increases bioenergetic functions in NPCs and decreases them in astrocytes. (a) Calculated values of OCR, ECAR, and the metabolic potentials ([stressed OCR or ECAR/baseline OCR or ECAR] x 100%)) from control (n = 9) and LOAD NPCs (n = 9) and control (n = 9) and LOAD astrocytes (n = 9) plotted as percent change after treatment with NR+Caff for 24 h. (b) the same data as shown in (a) plotted as percent change LOAD over controls in untreated and NR+Caff treated conditions. Data are means ± SEM from two repeat experiments. *p < 0.1; **p < 0.05; ***p < 0.01 using one‐way ANOVA, depicting significant changes between treated and untreated cells or groups