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Observation of invasive behavior and evaluation of invasive ability about cancer cells with (HUVECs) and without (control) self-assembled microvascular networks on day 12. (a) The invasion image of MDA-MB-231-GFP cells on day 12; HUVECs: with RFP; HMCAF: no fluorescence; and scale bar: 500 μm. (b) The number of invaded cancer cells and (c) the average invasion distance toward the matrix area (n = 3). Ns: not significant.
