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. 2022 Jul 15;132(14):e150097. doi: 10.1172/JCI150097

Figure 1. Identification of PIB from IFC patients.

Figure 1

(A) Typical morphology of PIB colonies. (B) Individual PIB. Scale bar: 1 μm. (C) Representative contraction tracings before and after treatment with PIB culture supernatant. (D and E) Quantification of the contraction in C (n = 6). (F–I) Representative contraction tracings of PIB culture supernatant–pretreated colons after stimulation with 87 mM KCl (F and G) or 100 μM ACh (H and I). PIB culture supernatant was applied over 15 minutes before stimulating with KCl or ACh. The experiments were repeated at least 3 times. Data are presented as mean ± SD. *P < 0.05, **P < 0.01 (paired 2-tailed t test).