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. 2022 Jul 7;2022:3862122. doi: 10.1155/2022/3862122

Figure 5.

Figure 5

The regulation of miR-100-5p affected the effects of HUCMSCs on inflammation, oxidative stress, and cell pyroptosis in vitro model of premature ovarian failure IL-1β and IL-1α levels (a, b), ROS production levels (c), MDA level (d), SOD (e), CAT (f), and GSH-px (j) levels, cell growth (g), LDH activity levels (h), JC-1 disaggregation (i), PI levels (k), and calcein-AM/CoCl2 (l). Vector: negative control + HUCMSC group; miR-100-5p: overexpression of miR-100-5p + HUCMSC group; sh-nc: sh-negative control + HUCMSC group; sh-miR-100-5p: downregulation of miR-100-5p + HUCMSC group; ∗∗p < 0.01 compared with vector or sh-negative control group.